Precursor miRNA: mmu-mir-669a-7

Precursor miRNA

Precursor Name mmu-mir-669a-7
Genomic Location chr2:10486653-10486739 (+); nearby genomic features
Clustered miRNAs mmu-mir-669a-1,mmu-mir-669g,mmu-mir-669j,mmu-mir-467a-2,mmu-mir-466e,mmu-mir-669a-4,mmu-mir-467b,mmu-mir-466c-1,mmu-mir-669a-5,mmu-mir-467a-3,mmu-mir-466c-2,mmu-mir-669a-6,mmu-mir-467a-4,mmu-mir-466b-4,mmu-mir-669a-7,mmu-mir-467a-5,mmu-mir-466b-5,mmu-mir-669p-1,mmu-mir-467a-6,mmu-mir-466c-3,mmu-mir-669a-8,mmu-mir-467a-7,mmu-mir-466b-6,mmu-mir-669a-9,mmu-mir-467a-8,mmu-mir-466b-7,mmu-mir-669p-2 (within 10kb in genome)
NCBI GENE ID 100526536
miRBase ID MI0014061
Precursor Sequence 
u    a     g    gu        c     c    c   au
 gugc ugugu uaua  ugugugug auguu augu uau  u
 |||| ||||| ||||  |||||||| ||||| |||| |||  
 cacg acgca auau  acacacac uacaa uaca aua  u
a    a     a    gc        a     -    u   ag

Mature miRNA

Mature Name mmu-miR-669a-5p
Previous Name mmu-miR-669a
Mature Sequence 5' - aguugugugugcauguucaugucu - 3' (length = 24)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0003477
Similar miRNAs mmu-miR-669f-5p, mmu-miR-669l-5p, mmu-miR-669p-5p (sharing the same seed sequence with mmu-miR-669a-5p).

Mature miRNA

Mature Name mmu-miR-669a-3p
Mature Sequence 5' - acauaacauacacacacacguau - 3' (length = 23)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0017243
Similar miRNAs mmu-miR-669a-3-3p, mmu-miR-669o-3p (sharing the same seed sequence with mmu-miR-669a-3p).

References

  • miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. Crippa S, Cassano M, Messina G, Galli D, Galvez BG, Curk T, Altomare C, Ronzoni F, Toelen J, Gijsbers R, Debyser Z, Janssens S, Zupan B, Zaza A, Cossu G, Sampaolesi M. J Cell Biol. 2011 Jun 27;193(7):1197-212.

  • A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A. PLoS Biol. 2011 Jan 18;9(1):e1000582.

  • Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. Genes Dev. 2010 May 15;24(10):992-1009.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.