Precursor miRNA: mmu-mir-615

Precursor miRNA

Precursor Name mmu-mir-615
Genomic Location chr15:103014910-103015001 (+); nearby genomic features
NCBI GENE ID 751557
miRBase ID MI0005004
Precursor Sequence 
uc    -    c          uc     u        cu    g ug
  ggga gggg gggagggggg  cccgg gcucggau  cgag g  c
  |||| |||| ||||||||||  ||||| ||||||||  |||| |   u
  cccu cccc ccuucucccu  ggguc cgagccug  gcuu u  u
--    a    -          cu     -        --    g ua

Mature miRNA

Mature Name mmu-miR-615-3p
Previous Name mmu-miR-615
Mature Sequence 5' - uccgagccugggucucccucuu - 3' (length = 22)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0003783

References

  • Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis. Ji XY, Guo YX, Wang LB, Wu WC, Wang JQ, He J, Gao R, Rasouli J, Gao MY, Wang ZH, Xiao D, Zhang WF, Ciric B, Zhang Y, Li X. J Neuroinflammation. 2024 Jan 22;21(1):29.

  • Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis. Han B, Liu Y, Zhang Q, Liang L. J Proteomics. 2023 Mar 15;274:104777.

  • Ssc-MiR-21-5p and Ssc-MiR-615 Regulates the Proliferation and Apoptosis of Leydig Cells by Targeting SOX5. Tang Q, Zhang Y, Yue L, Ren H, Pan C. Cells. 2022 Jul 21;11(14):2253.

  • CircZNF609 is involved in the pathogenesis of focal segmental glomerulosclerosis by sponging miR-615-5p. Cui X, Fu J, Luan J, Qi H, Jiao C, Ran M, Wang D, Hao X, Zhang Y, Kopp JB, Pi J, Zhou H. Biochem Biophys Res Commun. 2020 Oct 20;531(3):341-349.

  • Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein. Miyamoto Y, Mauer AS, Kumar S, Mott JL, Malhi H. PLoS One. 2014 Oct 14;9(10):e109637.

  • Two microRNAs, miR-330 and miR-125b-5p, mark the juxtaglomerular cell and balance its smooth muscle phenotype. Medrano S, Monteagudo MC, Sequeira-Lopez ML, Pentz ES, Gomez RA. Am J Physiol Renal Physiol. 2012 Jan 1;302(1):F29-37.

  • A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Prosser HM, Koike-Yusa H, Cooper JD, Law FC, Bradley A. Nat Biotechnol. 2011 Aug 7;29(9):840-5.

  • Regulation of mouse stomach development and Barx1 expression by specific microRNAs. Kim BM, Woo J, Kanellopoulou C, Shivdasani RA. Development. 2011 Mar;138(6):1081-6.

  • A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A. PLoS Biol. 2011 Jan 18;9(1):e1000582.

  • miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, Griffiths-Jones S. Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7.

  • Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. Genes Dev. 2010 May 15;24(10):992-1009.

  • MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing. Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A. Mol Hum Reprod. 2010 Jul;16(7):463-71.

  • A mammalian microRNA expression atlas based on small RNA library sequencing. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foà R, Schliwka J, Fuchs U, Novosel A, Müller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G, Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN, Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo JJ, Sander C, Zavolan M, Tuschl T. Cell. 2007 Jun 29;129(7):1401-14.

  • The expression profile of microRNAs in mouse embryos. Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K, Mirochnitchenko O, Inouye M, Kato I. Nucleic Acids Res. 2006 Mar 31;34(6):1765-71.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.