Mature miRNA: hsa-miR-5010-5p

Mature miRNA

miRNA Name hsa-miR-5010-5p
miRNA Sequence 5' - agggggauggcagagcaaaauu - 3' (length = 22)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0021043
Similar miRNAs hsa-miR-4525 (sharing the same seed sequence with hsa-miR-5010-5p).

Precursor miRNA

Precursor Name hsa-mir-5010
Genomic Location chr17:42514188-42514307 (+); nearby genomic features
NCBI GENE ID 100847046
miRBase ID MI0017878
Precursor Sequence 
gauc     a   c    --  --a         c   -          uggccuacagcugccucu   ca
    caggg acc uaga  gc   gggggaugg aga gcaaaauuca                  ugc  a
    ||||| ||| ||||  ||   ||||||||| ||| ||||||||||                  |||  
    guuuc ugg gucu  cg   ccccuuacc ucu uguuuuaggu                  acg  a
----     g   a    gu  aga         c   g          -----------------c   uc

References

  • MicroRNA-5010-5p ameliorates high-glucose induced inflammation in renal tubular epithelial cells by modulating the expression of PPP2R2D. Choi S, Sarker MK, Yu MR, Lee H, Kwon SH, Jeon JS, Noh H, Kim H. BMJ Open Diabetes Res Care. 2024 Mar 4;12(2):e003784.

  • RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation. Wu SF, Xia L, Shi XD, Dai YJ, Zhang WN, Zhao JM, Zhang W, Weng XQ, Lu J, Le HY, Tao SC, Zhu J, Chen Z, Wang YY, Chen S. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14395-14404.

  • Association of MicroRNAs and YRNAs With Platelet Function. Kaudewitz D, Skroblin P, Bender LH, Barwari T, Willeit P, Pechlaner R, Sunderland NP, Willeit K, Morton AC, Armstrong PC, Chan MV, Lu R, Yin X, Gracio F, Dudek K, Langley SR, Zampetaki A, de Rinaldis E, Ye S, Warner TD, Saxena A, Kiechl S, Storey RF, Mayr M. Circ Res. 2016 Feb 5;118(3):420-432.

  • Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. Joyce CE, Zhou X, Xia J, Ryan C, Thrash B, Menter A, Zhang W, Bowcock AM. Hum Mol Genet. 2011 Oct 15;20(20):4025-40.

  • Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. Hansen TB, Kjems J, Bramsen JB. RNA Biol. 2011 May-Jun;8(3):378-83.

  • miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, Griffiths-Jones S. Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.