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miRDB is an online database for miRNA target prediction and functional annotations in animals. All the targets were predicted by a bioinformatics tool called MirTarget2, which was developed by analyzing thousands of genes downregulated by miRNAs with an SVM learning machine. Common features associated with miRNA target binding have been identified and used to predict miRNA targets. miRDB hosts predicted miRNA targets in five species: human, mouse, rat, dog and chicken.

Besides target prediction, miRDB also provides a wiki interface for miRNA functional annotations. miRNA research is an exciting and rapidly evolving field. As a result, it is challenging for any single team to keep track of all the latest development on miRNA. By providing an open platform using the wiki model, we invite all miRNA researchers to continuously provide miRNA functional annotations and actively interact with each other. This is a new attempt whose success critically depends on the generous intellectual contributions from many miRNA researchers. A comprehensive and interactive catalog of miRNA functions will be a great asset to the whole miRNA community. Click here to start contributing today!

Click here to contact us with questions or comments about this web site. Last modified: February 05, 2008