Mature miRNA: hsa-miR-7977

Mature miRNA

miRNA Name hsa-miR-7977
miRNA Sequence 5' - uucccagccaacgcacca - 3' (length = 18)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0031180

Precursor miRNA

Precursor Name hsa-mir-7977
Genomic Location chr3:176515103-176515151 (+); nearby genomic features
NCBI GENE ID 102465858
miRBase ID MI0025753
Precursor Sequence 
--   -    c     c   aaaaa
  uuc ccag caacg acc     u
  ||| |||| ||||| |||     
  aag gguc guugu ugg     g
ca   a    u     c   guaua

References

  • Plasma exosomal Chen L, Wang K, Li L, Zheng B, Zhang Q, Zhang F, Chen J, Wang S. Future Oncol. 2022 Aug;18(26):2919-2931.

  • Overexpression of miR-7977 in CD4+ T cells is associated with multiplex autoimmunity in patients with Addison's disease. Fichna M, Å»urawek M, P Fichna J, RuchaÅ‚a M. Eur J Endocrinol. 2021 May 28;185(1):145-154.

  • Serum exosomal miR-7977 as a novel biomarker for lung adenocarcinoma. Chen L, Cao P, Huang C, Wu Q, Chen S, Chen F. J Cell Biochem. 2020 Jun;121(5-6):3382-3391.

  • miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells. Yoshida M, Horiguchi H, Kikuchi S, Iyama S, Ikeda H, Goto A, Kawano Y, Murase K, Takada K, Miyanishi K, Kato J, Kobune M. PLoS One. 2019 Mar 5;14(3):e0213220.

  • Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms. Horiguchi H, Kobune M, Kikuchi S, Yoshida M, Murata M, Murase K, Iyama S, Takada K, Sato T, Ono K, Hashimoto A, Tatekoshi A, Kamihara Y, Kawano Y, Miyanishi K, Sawada N, Kato J. Haematologica. 2016 Apr;101(4):437-47.

  • Research resource: small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes. Velthut-Meikas A, Simm J, Tuuri T, Tapanainen JS, Metsis M, Salumets A. Mol Endocrinol. 2013 Jul;27(7):1128-41.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.