Mature miRNA: hsa-miR-6500-3p

Mature miRNA

miRNA Name hsa-miR-6500-3p
miRNA Sequence 5' - acacuuguugggaugaccugc - 3' (length = 21)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0025455

Precursor miRNA

Precursor Name hsa-mir-6500
Genomic Location chr1:51060018-51060103 (+); nearby genomic features
Clustered miRNAs hsa-mir-4421,hsa-mir-6500 (within 10kb in genome)
NCBI GENE ID 102466656
miRBase ID MI0022211
Precursor Sequence 
           aa   agc     a uc         -u    u
ccugccugcag  agg   uaucc c  caggugucc  uucu c
|||||||||||  |||   ||||| |  |||||||||  |||| 
ggauggacguc  ucc   guagg g  guucacagg  gaga u
           cg   --a     - uu         uc    g

References

  • Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas. Liang ML, Hsieh TH, Ng KH, Tsai YN, Tsai CF, Chao ME, Liu DJ, Chu SS, Chen W, Liu YR, Liu RS, Lin SC, Ho DM, Wong TT, Yang MH, Wang HW. Oncotarget. 2016 Apr 12;7(15):19723-37.

  • Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. Joyce CE, Zhou X, Xia J, Ryan C, Thrash B, Menter A, Zhang W, Bowcock AM. Hum Mol Genet. 2011 Oct 15;20(20):4025-40.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.