Mature miRNA: hsa-miR-643

Mature miRNA

miRNA Name hsa-miR-643
miRNA Sequence 5' - acuuguaugcuagcucagguag - 3' (length = 22)
Predicted Targets miRDB
Validated Targets TarBase
Targeted Pathways miRDB
miRBase ID MIMAT0003313

Precursor miRNA

Precursor Name hsa-mir-643
Genomic Location chr19:52281797-52281893 (+); nearby genomic features
NCBI GENE ID 693228
miRBase ID MI0003658
Precursor Sequence 
accaaguga      u                a        a   gg gu
         uauuca ugucuaccugagcuag auacaagu guu  c  c
         |||||| |||||||||||||||| |||||||| |||  |   u
         guaagu auagauggacucgauc uauguuca cag  g  u
----aaaaa      u                g        -   -a ac

References

  • CircRNA circFADS2 is Downregulated in Endometritis and its Overexpression Promotes miR-643 Maturation in Human Endometrial Epithelial Cells to Suppress Cell Apoptosis. Liang Y, Ming Q, Shen T, Jin Y, Zhao X, Luo R, Wang J, Lu J. Reprod Sci. 2021 Dec;28(12):3508-3514.

  • MiR-643 Functions as a Potential Tumor Suppressor in Gastric Cancer by Inhibiting Cell Proliferation and Invasion Wu Y, Ye H, Peng B, Jiang H, Tang Q, Liu Y, Xi J, Chen S. Ann Clin Lab Sci. 2021 Jul;51(4):494-502.

  • MiR-643 inhibits lipopolysaccharide-induced endometritis progression by targeting TRAF6. Zhao R, Wang J, Zhang X, Chen Y. Cell Biol Int. 2020 Apr;44(4):1059-1067.

  • Entamoeba histolytica López-Rosas I, López-Camarillo C, Salinas-Vera YM, Hernández-de la Cruz ON, Palma-Flores C, Chávez-Munguía B, Resendis-Antonio O, Guillen N, Pérez-Plasencia C, Álvarez-Sánchez ME, Ramírez-Moreno E, Marchat LA. Front Cell Infect Microbiol. 2019 Jan 8;8:437.

  • miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, Griffiths-Jones S. Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7.

  • The colorectal microRNAome. Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3687-92.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.