Mature miRNA: hsa-miR-4721

Mature miRNA

miRNA Name hsa-miR-4721
miRNA Sequence 5' - ugagggcuccaggugacggugg - 3' (length = 22)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0019835

Precursor miRNA

Precursor Name hsa-mir-4721
Genomic Location chr16:28843919-28844007 (-); nearby genomic features
NCBI GENE ID 100616256
miRBase ID MI0017356
Precursor Sequence 
ggg    g    g    agcca     -    -aa   -     a
   ccug ucau guca     gguuc cauc   gcc ccacc g
   |||| |||| ||||     ||||| ||||   ||| ||||| 
   ggac ggug cagu     ucggg gugg   cgg ggugg a
uug    g    g    ggacc     a    acc   a     a

References

  • A direct negative feedback loop of miR-4721/FOXA1/Nanog promotes nasopharyngeal cell stem cell enrichment and metastasis. Zhao M, Tang Z, Wang Y, Ding J, Guo Y, Gao T. J Transl Med. 2021 Sep 9;19(1):387.

  • Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C. Cancer Res. 2011 Jan 1;71(1):78-86.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.