Mature miRNA: hsa-miR-412-5p

Mature miRNA

miRNA Name hsa-miR-412-5p
miRNA Sequence 5' - uggucgaccaguuggaaaguaau - 3' (length = 23)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0026557

Precursor miRNA

Precursor Name hsa-mir-412
Genomic Location chr14:101065447-101065537 (+); nearby genomic features
Clustered miRNAs hsa-mir-323b,hsa-mir-154,hsa-mir-496,hsa-mir-377,hsa-mir-541,hsa-mir-409,hsa-mir-412,hsa-mir-369,hsa-mir-410,hsa-mir-656 (within 10kb in genome)
NCBI GENE ID 574433
miRBase ID MI0002464
Precursor Sequence 
----cug      gg      a    c      u   aa    -    u
       ggguac  ggaugg uggu gaccag ugg  agua auug u
       ||||||  |||||| |||| |||||| |||  |||| |||| 
       ccuaug  ccugcc auca cugguc acu  ucau uaau u
gacgucg      --      g    c      c   --    g    c

References

  • Long non-coding RNA MBNL1-AS1 regulates proliferation, migration, and invasion of cancer stem cells in colon cancer by interacting with MYL9 via sponging microRNA-412-3p. Zhu K, Wang Y, Liu L, Li S, Yu W. Clin Res Hepatol Gastroenterol. 2020 Feb;44(1):101-114.

  • miR-412-5p targets Xpo1 to regulate angiogenesis in hemorrhoid tissue. Wang C, Lu H, Luo C, Song C, Wang Q, Peng Y, Xin Y, Liu T, Yang W. Gene. 2019 Jul 15;705:167-176.

  • The repertoire and features of human platelet microRNAs. PlĂ© H, Landry P, Benham A, Coarfa C, Gunaratne PH, Provost P. PLoS One. 2012;7(12):e50746.

  • miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, Griffiths-Jones S. Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.

  • Clustering and conservation patterns of human microRNAs. Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H. Nucleic Acids Res. 2005 May 12;33(8):2697-706.