Mature miRNA: hsa-miR-2682-3p



Mature miRNA

miRNA Name hsa-miR-2682-3p
Previous Name hsa-miR-2682*
miRNA Sequence 5' - cgccucuucagcgcugucuucc - 3' (length = 22)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0013518
Similar miRNAs hsa-miR-6781-3p (sharing the same seed sequence with hsa-miR-2682-3p).

Precursor miRNA

Precursor Name hsa-mir-2682
Genomic Location chr1:98045242-98045351 (-); nearby genomic features
Clustered miRNAs hsa-mir-2682,hsa-mir-137 (within 10kb in genome)
NCBI GENE ID 100616452
miRBase ID MI0012063
Precursor Sequence
-------ac u       ---      u    c        a   uuc  a     aauc
         c uccugaa   agaggu gggg aggcagug cug   ag cgucc    u
         | |||||||   |||||| |||| |||||||| |||   || |||||    
         g aggauuu   ucuccg cccu ucugucgc gac   uc gcagg    c
aaacucuga c       ccg      u    -        -   uuc  c     guuu

References


  • miR-2682-3p antagonizes its host lncRNA-MIR137HG by interacting with the same target FUS to regulate the progression of gastric cancer. Du Y, Chen Y, Wu T, Fan X, Lin W, Jiang Z. BMC Cancer. 2022 Jun 22;22(1):689.

  • MIR137/MIR2682 locus is associated with perineural invasiveness in head and neck cancer. ÄŒeleÅ¡nik H, Büdefeld T, ÄŒizmarević B, Å vagan M, Potočnik U. J Oral Pathol Med. 2021 Oct;50(9):874-881.

  • SNHG3/miR-2682-5p/HOXB8 promotes cell proliferation and migration in oral squamous cell carcinoma. Lu N, Yin Y, Yao Y, Zhang P. Oral Dis. 2021 Jul;27(5):1161-1170.

  • ELK1/lncRNA-SNHG7/miR-2682-5p feedback loop enhances bladder cancer cell growth. Wang W, Chen S, Song X, Gui J, Li Y, Li M. Life Sci. 2020 Dec 1;262:118386.

  • A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. Duan J, Shi J, Fiorentino A, Leites C, Chen X, Moy W, Chen J, Alexandrov BS, Usheva A, He D, Freda J, O'Brien NL; Molecular Genetics of Schizophrenia collaboration; Genomic Psychiatric Cohort consortium; McQuillin A, Sanders AR, Gershon ES, DeLisi LE, Bishop AR, Gurling HM, Pato MT, Levinson DF, Kendler KS, Pato CN, Gejman PV. Am J Hum Genet. 2014 Dec 4;95(6):744-53.

  • miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Friedländer MR, Mackowiak SD, Li N, Chen W, Rajewsky N. Nucleic Acids Res. 2012 Jan;40(1):37-52.

  • Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C. Cancer Res. 2011 Jan 1;71(1):78-86.

  • miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, Griffiths-Jones S. Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7.

  • Discovery of novel microRNAs in female reproductive tract using next generation sequencing. Creighton CJ, Benham AL, Zhu H, Khan MF, Reid JG, Nagaraja AK, Fountain MD, Dziadek O, Han D, Ma L, Kim J, Hawkins SM, Anderson ML, Matzuk MM, Gunaratne PH. PLoS One. 2010 Mar 10;5(3):e9637.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.