Mature miRNA: hsa-miR-1208

Mature miRNA

miRNA Name hsa-miR-1208
miRNA Sequence 5' - ucacuguucagacaggcgga - 3' (length = 20)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0005873

Precursor miRNA

Precursor Name hsa-mir-1208
Genomic Location chr8:128150116-128150188 (+); nearby genomic features
NCBI GENE ID 100302281
miRBase ID MI0006341
Precursor Sequence 
-     g   -aauc   gu     ca    -    cg
 caccg cag     acu  ucaga  ggcg gaga  g
 ||||| |||     |||  |||||  |||| ||||  
 guggu guc     uga  agucu  ccgc cuuu  g
g     -   accac   gu     -c    u    cu

References

  • Focused ultrasound combined with miR-1208-equipped exosomes inhibits malignant progression of glioma. Zhan Y, Song Y, Qiao W, Sun L, Wang X, Yi B, Yang X, Ji L, Su P, Zhao W, Liu Z, Ren W. Br J Cancer. 2023 Oct;129(7):1083-1094.

  • Genetic polymorphisms in MIR1208 and MIR5708 are associated with susceptibility to COPD in the Chinese population. Zhou Y, Bai F, Li X, Zhou G, Tian X, Li G, Zhang Y, Zhou X, Xu D, Ding Y. Pulmonology. 2023 Jan-Feb;29(1):6-12.

  • HAND2-AS1 targeting miR-1208/SIRT1 axis alleviates foam cell formation in atherosclerosis. Ma L, He S, Li H, Zhang S, Yin Y. Int J Cardiol. 2022 Jan 1;346:53-61.

  • Silencing circPVT1 enhances radiosensitivity in non-small cell lung cancer by sponging microRNA-1208. Huang M, Li T, Wang Q, Li C, Zhou H, Deng S, Lv Z, He Y, Hou B, Zhu G. Cancer Biomark. 2021;31(3):263-279.

  • MiR-1208 Increases the Sensitivity to Cisplatin by Targeting TBCK in Renal Cancer Cells. Kim EA, Jang JH, Sung EG, Song IH, Kim JY, Lee TJ. Int J Mol Sci. 2019 Jul 19;20(14):3540.

  • Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. Wolpin BM, Rizzato C, Kraft P, Kooperberg C, Petersen GM, Wang Z, Arslan AA, Beane-Freeman L, Bracci PM, Buring J, Canzian F, Duell EJ, Gallinger S, Giles GG, Goodman GE, Goodman PJ, Jacobs EJ, Kamineni A, Klein AP, Kolonel LN, Kulke MH, Li D, Malats N, Olson SH, Risch HA, Sesso HD, Visvanathan K, White E, Zheng W, Abnet CC, Albanes D, Andreotti G, Austin MA, Barfield R, Basso D, Berndt SI, Boutron-Ruault MC, Brotzman M, Büchler MW, Bueno-de-Mesquita HB, Bugert P, Burdette L, Campa D, Caporaso NE, Capurso G, Chung C, Cotterchio M, Costello E, Elena J, Funel N, Gaziano JM, Giese NA, Giovannucci EL, Goggins M, Gorman MJ, Gross M, Haiman CA, Hassan M, Helzlsouer KJ, Henderson BE, Holly EA, Hu N, Hunter DJ, Innocenti F, Jenab M, Kaaks R, Key TJ, Khaw KT, Klein EA, Kogevinas M, Krogh V, Kupcinskas J, Kurtz RC, LaCroix A, Landi MT, Landi S, Le Marchand L, Mambrini A, Mannisto S, Milne RL, Nakamura Y, Oberg AL, Owzar K, Patel AV, Peeters PH, Peters U, Pezzilli R, Piepoli A, Porta M, Real FX, Riboli E, Rothman N, Scarpa A, Shu XO, Silverman DT, Soucek P, Sund M, Talar-Wojnarowska R, Taylor PR, Theodoropoulos GE, Thornquist M, Tjønneland A, Tobias GS, Trichopoulos D, Vodicka P, Wactawski-W… Nat Genet. 2014 Sep;46(9):994-1000.

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N; Breast and Ovarian Cancer Susceptibility Collaboration; Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); van der Luijt RB, Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, Müller-Myhsok B, Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van der Schoot CE, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso MR, Cox A, Bro… Nat Genet. 2013 Apr;45(4):353-61, 361e1-2.

  • Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Sakashita M, Yamada T, Fujieda S, Tanaka S, Doi S, Miyatake A, Enomoto T, Nishiyama C, Nakano N, Maeda K, Okumura K, Ogawa H, Ikeda S, Noguchi E, Sakamoto T, Hizawa N, Ebe K, Saeki H, Sasaki T, Ebihara T, Amagai M, Takeuchi S, Furue M, Nakamura Y, Tamari M. Nat Genet. 2012 Nov;44(11):1222-6.

  • The identification of microRNAs in a genomically unstable region of human chromosome 8q24. Huppi K, Volfovsky N, Runfola T, Jones TL, Mackiewicz M, Martin SE, Mushinski JF, Stephens R, Caplen NJ. Mol Cancer Res. 2008 Feb;6(2):212-21.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.