Mature miRNA: hsa-miR-1197

Mature miRNA

miRNA Name hsa-miR-1197
miRNA Sequence 5' - uaggacacauggucuacuucu - 3' (length = 21)
Predicted Targets miRDB
Validated Targets TarBase
miRBase ID MIMAT0005955

Precursor miRNA

Precursor Name hsa-mir-1197
Genomic Location chr14:101025564-101025651 (+); nearby genomic features
Clustered miRNAs hsa-mir-379,hsa-mir-411,hsa-mir-299,hsa-mir-380,hsa-mir-1197,hsa-mir-323a,hsa-mir-758,hsa-mir-329-1,hsa-mir-329-2,hsa-mir-494,hsa-mir-1193,hsa-mir-543,hsa-mir-495 (within 10kb in genome)
NCBI GENE ID 100302250
miRBase ID MI0006656
Precursor Sequence 
acuuccu      -u     ugc   u       gug g    - uuu
       gguauu  gaaga   ggu gaccaug   u uacg c   a
       ||||||  |||||   ||| |||||||   | |||| |    u
       cuauaa  cuucu   uca cugguac   g augc g   u
------a      cu     ---   u       aca g    a ugu

References

  • Circular RNA hsa_circ_0075542 acts as a sponge for microRNA-1197 to suppress malignant characteristics and promote apoptosis in prostate cancer cells. Han Y, Wen X, Li X, Chen D, Peng L, Lai B, Huang H. Bioengineered. 2021 Dec;12(1):5620-5631.

  • MicroRNA-1197 downregulation inhibits proliferation and migration in human non- small cell lung cancer cells by upregulating HOXC11. Sun B, Hua J, Cui H, Liu H, Zhang K, Zhou H. Biomed Pharmacother. 2019 Sep;117:109041.

  • miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, Griffiths-Jones S. Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7.

  • New miRNAs cloned from neuroblastoma. Afanasyeva EA, Hotz-Wagenblatt A, Glatting KH, Westermann F. BMC Genomics. 2008 Jan 29;9:52.

  • miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.